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Sauvagine

Product ID S0381
Cas No. 74434-59-6
Purity ≥98%
Product Unit SizeCostQuantityStock
0.5 mg $460.00 In stock
1 mg $782.50 Please Inquire
2.5 mg $1,149.50 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

Sauvagine is a corticotropin-releasing factor (CRF)-family peptide found in amphibians; it exhibits diuretic, vasodilatory, and neuromodulatory activities and is involved in growth, stress, anxiety, and many other hormonal signaling pathways. Sauvagine induces vasodilation in rat thoracic aortas, potentially through prolonged activation of NOS. Additionally, sauvagine increases striatal tyrosine hydroxylase activity in a Ca2+-dependent manner.

Product Info

Cas No.

74434-59-6

Purity

≥98%

Formula

C202H347N56O63S

Formula Wt.

4599.4

Synonym

Sauvagin

Solubility

Soluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

S0381 MSDS PDF

Info Sheet

S0381 Info Sheet PDF

References

Lovejoy DA, Balment RJ. Evolution and physiology of the corticotropin-releasing factor (CRF) family of neuropeptides in vertebrates. Gen Comp Endocrinol. 1999 Jul;115(1):1-22. PMID: 10375459.

Barker DM, Corder R. Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. Br J Pharmacol. 1999 Jan;126(1):317-25. PMID: 10051151.

Onali P, Olianas MC. CRF-like effects of sauvagine and urotensin I on synaptosomal tyrosine hydroxylase activity of mouse striatum. Brain Res. 1990 Sep 3;526(2):181-5. PMID: 1979515.

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