• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register

Fluphenazine Hydrochloride

Product ID F4584
Cas No. 146-56-5
Purity ≥97%
Product Unit SizeCostQuantityStock
250 mg $53.00 In stock
1 g $105.90 In stock
5 g $220.50 In stock
25 g $500.00 In stock
Bulk Quote
Add to Wishlist

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Fluphenazine is a typical piperazine antipsychotic that is clinically used to treat schizophrenia, bipolar disorder, and dementia. Fluphenazine acts as an antagonist at D2 receptors. Fluphenazine also exhibits arrhythmogenic activity, increasing action potential duration and inducing QT prolongation by decreasing current amplitude of human ether-related-a-go-go (hERG) K+ channels. This compound acts as a functional inhibitor of acid sphingomyelinase (FIASMA).

Product Info

Cas No.

146-56-5

Purity

≥97%

Formula

C22H26F3N3OS • 2HCl

Formula Wt.

510.44

Chemical Name

1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)phenothiazin- 10-yl)propyl)-

IUPAC Name

2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl] ethanol;dihydrochloride

Synonym

Dapotum, Elinol, Fluorfenazine, Fluorophenazine, Pacinol, Moditen.

Solubility

Soluble in water (>100 mg/L), ethanol (149 mg/mL)

Appearance

White or near-white crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F4584 MSDS PDF

Info Sheet

F4584 Info Sheet PDF

References

Hong HK, Lee BH, Park MH, et al. Block of hERG K+ channel and prolongation of action potential duration by fluphenazine at submicromolar concentration. Eur J Pharmacol. 2013 Feb 28;702(1-3):165-73. PMID: 23395964.

Pickar D, Owen RR, Litman RE, et al. Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine. Arch Gen Psychiatry. 1992 May;49(5):345-53. PMID: 1375019.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2023 LKT Laboratories, All Rights Reserved - Products for research use only