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Indoximod

Indoximod

Product ID I525138
Cas No. 110117-83-4
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $57.10 In stock
1 g $165.40 In stock
10 g $1,232.10 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Indoximod is an inhibitor of indoleamine 2,3 dioxygenase, which plays a role in immune regulation. Indoximod has been found to enhance inflammatory cytokines IL-1beta and IL-6 expression in human corneal epithelial cells exposed to inactivated A. fumigatus spores. Indoximod has also been found as a metabolite in tomato plants exposed to fungi or bacteria.

Product Info

Cas No.

110117-83-4

Purity

≥98%

Formula

C12H14N2O2

Formula Wt.

218.26

IUPAC Name

(2R)-2-amino-3-(1-methylindol-3-yl)propanoic acid

Synonym

NLG-8189, 1-Methyl-D-tryptophan,

Solubility

DMSO:1 mg/mL warmed (4.58 mM) Water:Insoluble Ethanol:Insoluble

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

I525138 MSDS PDF

Info Sheet

I525138 Info Sheet PDF

References

Soliman HH, Minton SE, Han HS, et al. A phase I study of indoximod in patients with advanced malignancies. Oncotarget. 2016 Apr 19;7(16):22928-22938. PMID: 27008709

Jiang N, Zhao G, Lin J, et al. Indoleamine 2,3-dioxygenase is involved in the inflammation response of corneal epithelial cells to aspergillus fumigatus infections. PLoS One. 2015 Sep 11;10(9):e0137423. PMID: 26361229

Camanes G, Scalschi L, Vicedo B, et al. An untargeted global metabolomic analysis reveals the biochemical changes underlying basal resistance and priming in Solanum lycopersicum, and identifies 1-methyltryptophan as a metabolite involved in plant responses to Botrytis cinerea and Pseudomonas syringae. Plant J. 2015 Oct;84(1):125-139. PMID: 26270176

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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