• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Fluoxetine Hydrochloride

Fluoxetine Hydrochloride

Product ID F4780
Cas No. 56296-78-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $96.00 In stock
5 g $382.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Fluoxetine is an SSRI most often used to treat mood or psychiatric disorders such as depression, obsessive compulsive disorder, bulimia nervosa, panic disorder, and PTSD. Fluoxetine inhibits 5-HT reuptake acting as an antagonist at 5-HT transporters (SERTs) as well as at 5-HT receptors and σ1 receptors. Likely related to its antidepressant activities, fluoxetine can prevent cue- and stress-induced reinstatement in animal models of substance abuse. In a clinical setting, fluoxetine increased abstinence rates in former female heroin-dependent subjects when combined with naltrexone compared to naltrexone alone. Additionally, this compound exhibits antiviral activity, demonstrated by its ability to reduce synthesis of coxsackievirus RNA and protein. Fluoxetine also acts as a functional inhibitor of acid sphingomyelinase (FIASMA).

pH value: 5-7 (5% aqueous solution)

Product Info

Cas No.

56296-78-7

Purity

≥98%

Formula

C17H18F3NO • HCl

Formula Wt.

345.79

Chemical Name

N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzene- propanamine hydrochloride

IUPAC Name

N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine; hydrochloride

Synonym

Adofen, Fluoxeren, Lovan, Prozac, Sarafem

Melting Point

158.4-158.9°C

Solubility

Soluble in methanol, ethanol, acetone, acetonitrile and chloroform. Water to 10 mM, DMSO to 100 mM. DMF to 16 mg/mL.Ethanol to 69mg/mL

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F4780 MSDS PDF

Info Sheet

F4780 Info Sheet PDF

References

Zuo J, Quinn KK, Kye S, et al. Fluoxetine is a potent inhibitor of coxsackievirus replication. Antimicrob Agents Chemother. 2012 Sep;56(9):4838-44. PMID: 22751539.

Apparsundaram S, Stockdale DJ, Henningsen RA, et al. Antidepressants targeting the serotonin reuptake transporter act via a competitive mechanism. J Pharmacol Exp Ther. 2008 Dec;327(3):982-90. PMID: 18801947.

Krupitsky EM, Zvartau EE, Masalov DV, et al. Naltrexone with or without fluoxetine for preventing relapse to heroin addiction in St. Petersburg, Russia. J Subst Abuse Treat. 2006 Dec;31(4):319-28. PMID: 17084785.

Pälvimäki EP, Roth BL, Majasuo H, et al. Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor. Psychopharmacology (Berl). 1996 Aug;126(3):234-40. PMID: 8876023.

Narita N, Hashimoto K, Tomitaka S, et al. Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain. Eur J Pharmacol. 1996 Jun 20;307(1):117-9. PMID: 8831113.

Opal MD, Klenotich SC, Morais M, et al. Serotonin 2C receptor antagonists induce fast-onset antidepressant effects. Mol Psychiatry. 2014 Oct;19(10):1106-1114. PMID: 24166413.

Nagano M, Liu M, Inagaki H, et al. Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasone. Neuropharmacology. 2012 Aug;63(2):292-300. PMID: 22710353.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D3447

    Diltiazem Hydrochloride

    Benzothiazepine; L-type Ca2+ channel blocker, p...

    ≥98%
  • P3592

    Pixantrone Dimaleate

    Aza-anthracenedione, DNA intercalator; topoisom...

    ≥98%
  • A0822

    N-Acetyl-S-(N-methylsulfinylbutylthiocarbamoyl)-L-cysteine

    Sulforaphane-cysteine conjugate.

    ≥98%
  • S1845

    L-(+)-Selenomethionine

    Naturally occurring amino acid found in grains,...

    ≥98%
  • Z161025

    β-Zearalenol

    Mycotoxin that has structural similarity to est...

    ≥98%
  • G4596

    Glycidamide

    Epoxide metabolite of acrylamide, induces DNA a...

    ≥98%
  • O1176

    n-Octyl Caffeate

    Caffeic acid derivative.

    ≥98%
  • G4484

    Glucagon-like Peptide II, rat

    Endogenous peptide hormone, involved in intesti...

    ≥95%
  • P1952

    Penitrem A

    Neuroactive mycotoxin produced by Penicillum an...

    ≥97%
  • F4420

    Boc-FLFLF

    Peptide; FRP1 antagonist.

    ≥95%
  • L1881

    Leuprolide Acetate

    GnRH analog; GnRH1 agonist.

    ≥95%
  • C002041

    Cabazitaxel

    Taxoid that disrupts the microtubular network i...

    ≥98%
  • D3208

    Diclazuril

    Coccidiostat, GAPDH inhibitor.

    ≥98%
  • C0160

    Canrenone

    Metabolite of spironolactone; Na+/K+ ATPase par...

    ≥98%
  • A761003

    AT-7519 Hydrochloride

    ATP competitive CDK inhibitor.

    ≥98%
  • A2050

    Aflatoxin G2

    Mycotoxin produced by species of Aspergillus; D...

    ≥98%
  • A6818

    Arenobufagin

    Bufanolide steroid found in Bufo arenarum;VEGFR...

    ≥98%
  • L0400

    LB-100

    PP2A inhibitor.

    ≥98%
  • P8168

    Puromycin Dihydrochloride

    Protein synthesis inhibitor, DPP2 and metallope...

    ≥98%
  • P9200

    PX-866

    Wortmannin analog; PI3K inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only