Name: Canrenone
SKU: C0160
Availability: InStock

Description

Canrenone is an active metabolite of spironolactone that acts as an aldosterone antagonist, anti-androgen, and diuretic. Canrenone acts as a partial agonist on the Na+/K+ ATPase.

Product Info

Cas No.	976-71-6
Purity	≥98%
Formula	C₂₂H₂₈O₃
Formula Wt.	340.46
Chemical Name	(17α)-17-Hydroxy-3-oxo-pregna-4,6-diene-21- carboxylic acid γ-lactone
IUPAC Name	10,13-dimethylspiro[2,8,9,11,12,14,15, 16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
Synonym	Phanurane
Melting Point	149-151°C
Appearance	Light yellow crystal powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	C0160 MSDS PDF
Info Sheet	C0160 Info Sheet PDF

References

Cargnelli G, Trevisi L, Debetto P, et al. Effects of canrenone on aorta and right ventricle of the rat. J Cardiovasc Pharmacol. 2001 May;37(5):540-7. PMID: 11336105.

Corvol P, Claire M, Oblin ME, et al. Mechanism of the antimineralocorticoid effects of spirolactones. Kidney Int. 1981 Jul;20(1):1-6. PMID: 7029118.

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Canrenone

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