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Rifapentine

Rifapentine

Product ID R327201
Cas No. 61379-65-5
Purity ≥97%
Product Unit SizeCostQuantityStock
10 mg $71.70 In stock
25 mg $104.80 In stock
100 mg $275.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Rifapentine is an antibiotic shown to reduce infection and prevent reactivation of tuberculosis in infected macaques. A mouse model showed improved survival rate, alleviated clinical signs, reduced viral load, and reduced injury in target organs when treated with rifapentine.

Product Info

Cas No.

61379-65-5

Purity

≥97%

Formula

C47H64N4O12

Formula Wt.

877.05

IUPAC Name

[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-[(E)-(4-cyclopentylpiperazin-1-yl)iminomethyl]-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate

Synonym

Rifapentin, Cyclopentylrafampicin

Solubility

Soluble in MeOH, EtOH, Chloroform, acetone.

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

Info Sheet

R327201 Info Sheet PDF

References

Sharan R, Ganatra S, Singh D, et al. Isoniazid and rifapentine treatment effectively reduces persistant M. tuberculosis infection in macaque lungs. J Clin Invest. 2022 Sep 15;132(18):e161564. PMID: 35862216

Qian X, Wu B, Tang H, et al. Rifapentine is an entry and replication inhibitor against yellow fever virus both in vitro and in vivo. Emerg Microbes Infect. 2022 Dec;11(1):873-884. PMID: 35249454

Saini V, Ammerman N, Chang Y, et al. Treatment-shortening effect of a novel regimen combining clofazimine and high-dose rifapentine in pathologically distinct mouse models of tuberculosis. Antimicrob Agents Chemother. 2019 May 24;63(6):e00388-19. PMID: 30936097

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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