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Shikonin

Product ID S291333
Cas No. 517-89-5
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $58.90 In stock
50 mg $194.20 In stock
100 mg $347.30 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Shikonin is a natural naphthoquinone compound. It has anti-inflammatory, antibacterial, anti-tumor, and hypoglycemic activities. It has also been shown to induce necroptosis and chromatinolysis in glioma cells.

Product Info

Cas No.

517-89-5

Purity

≥98%

Formula

C16H16O5

Formula Wt.

288.29

Chemical Name

(-)-Shikonin

IUPAC Name

5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione

Synonym

Isoarnebin 4, (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione, (-)-Shikonin

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

S291333 MSDS PDF

Info Sheet

S291333 Info Sheet PDF

References

Huang B, Wang Q, Jiang L, et al. Shikonin ameliorated mice colitis by inhibiting dimerization and tetramerization of PKM2 in macrophages. Front Pharmacol. 2022 Aug 17;13:926945. PMID: 36059938.

Wang X, Fan L, Wang X, et al. Cyclophilin A contributes to shikonin-induced glioma cell necroptosis and promotion of chromatinolysis. Sci Rep. 2022 Aug 29;12(1):14675. PMID: 36038617.

Xu Z, Huang L, Zhang T, et al. Shikonin inhibits the proliferation of cervical cancer cells via FAK/AKT/GSK3beta signalling. Oncol Lett. 2022 Jul 8;24(3):304. PMID: 35949620.

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