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C-176

C-176

Product ID C000076
Cas No. 314054-00-7
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $60.70 In stock
25 mg $159.90 In stock
100 mg $435.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

C-176 is a covalent inhibitor of STING.

Product Info

Cas No.

314054-00-7

Purity

≥99%

Formula

C11H7IN2O4

Formula Wt.

358.09

IUPAC Name

N-(4-iodophenyl)-5-nitrofuran-2-carboxamide

Synonym

STING Inhibitor C-176, C176, C 176

Appearance

Yellow solid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

C000076 Info Sheet PDF

References

Yang M, Ma Y, Zhi Y, et al. Inhibitors of IFN gene stimulators (STING) improve intestinal ischemia-reperfusion-induced acute lung injury by activating AMPK signaling. Eur J Med Res. 2022 May 31;27(1):79. PMID: 35642042

Kong L, Li W, Wang W, et al. mtDNA-STING axis mediates microglial polarization via IRF3/NF-kappaB signaling after ischemic stroke. Front Immunol. 2022 Apr 5;13:860977. PMID: 35450066

Li X, Zhang Z, Yu Y, et al. Activation of the STING-IRF3 pathway involved in psoriasis with diabetes mellitus. J Cell Mol Med. 2022 Apr;26(8):2139-2151. PMID: 35174638

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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