Description
C-176 is a covalent inhibitor of STING.
Product Unit Size | Cost | Quantity | Stock |
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C-176 is a covalent inhibitor of STING.
Cas No. | 314054-00-7 |
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Purity | ≥99% |
Formula | C11H7IN2O4 |
Formula Wt. | 358.09 |
IUPAC Name | N-(4-iodophenyl)-5-nitrofuran-2-carboxamide |
Synonym | STING Inhibitor C-176, C176, C 176 |
Appearance | Yellow solid |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet |
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Yang M, Ma Y, Zhi Y, et al. Inhibitors of IFN gene stimulators (STING) improve intestinal ischemia-reperfusion-induced acute lung injury by activating AMPK signaling. Eur J Med Res. 2022 May 31;27(1):79. PMID: 35642042
Kong L, Li W, Wang W, et al. mtDNA-STING axis mediates microglial polarization via IRF3/NF-kappaB signaling after ischemic stroke. Front Immunol. 2022 Apr 5;13:860977. PMID: 35450066
Li X, Zhang Z, Yu Y, et al. Activation of the STING-IRF3 pathway involved in psoriasis with diabetes mellitus. J Cell Mol Med. 2022 Apr;26(8):2139-2151. PMID: 35174638
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