Description
Sulbactam is a β-lactamase inhibitor that is administered clinically to improve the efficacy of carbapenem antibiotics. Sulbactam is often administered to improve antibacterial efficacy against Enterobacter and Staphylococcus.
Product Unit Size | Cost | Quantity | Stock |
---|
Sulbactam is a β-lactamase inhibitor that is administered clinically to improve the efficacy of carbapenem antibiotics. Sulbactam is often administered to improve antibacterial efficacy against Enterobacter and Staphylococcus.
Cas No. | 68373-14-8 |
---|---|
Purity | ≥98% |
Formula | C8H11NO5S |
Formula Wt. | 233.25 |
Chemical Name | (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
IUPAC Name | (2S,5R)-3,3-dimethyl-4,4, 7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
Synonym | CP 45899 |
Melting Point | 148-151°C |
Solubility | Soluble in water, DMSO, ethanol, methanol, DMF. |
Appearance | Light Orange Powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Li R, Liao JM, Gu CR, et al. Theoretical investigation on reaction of sulbactam with wild-type SHV-1 β-lactamase: acylation, tautomerization, and deacylation. J Phys Chem B. 2011 Sep 1;115(34):10298-310. PMID: 21797222.
Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.
Induces apoptosis, DNA cleavage and strand brea...
Histamine H1-antagonist
Fluoroquinolone; topoisomerase IV and bacterial...
SERT inhibitor, potential voltage-gated K+ chan...
Found in Streptomyces; proteasome inhibitor.
α-glucosidase inhibitor.
Tropane alkaloid found in Solanaceae plants; mA...
Taxane synthesis intermediate.
ITC precursor found in cruciferous vegetables.<...
Trichothecene mycotoxin produced by Fusarium.
Endogenous quaternary ammonium, required for fa...
Synthesis impurity
Trihydroxybenzoic acid glycoside found in Berge...
Staurosporine analog; PKC inhibitor.
VEGFR inhibitor.
Thiazide-like diuretic; Kv7.1 and minK K+ chann...
Tropane alkaloid found in plants in the Solanac...
Glycosylated isoflavone found in soy; TAS2R ago...
Vinca alkaloid found in Catharanthus; microtubu...
ROCK inhibitor.