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Sinigrin Monohydrate, synthetic

Product ID S3453
Cas No.
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $175.00 In stock
250 mg $325.00 In stock
1 g $950.00 Please Inquire
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Sinigrin is an isothiocyanate precursor often found in vegetables belonging to the Brassicaceae family, such as Brussels sprouts, broccoli seeds, and mustard seeds. In vivo, sinigrin is converted to allyl isothiocyanate by endogenous myrosinase; allyl isothiocyanate exhibits a wide variety of beneficial qualities, including antioxidative, anti-hyperlipidemic, and anticancer activities. Sinigrin itself also has antioxidant activity in addition to its ability to modify lipid metabolism. Administration of sinigrin in vivo increases free fatty acids and esterified cholesterol and decreases triacylglycerol levels. Additionally, this compound induces expression of NAD(P)H:quinone oxidoreductase 1 and glutathione-S-transferase in the gastrointestinal tract in rodent models.

Product Info

Purity

≥98%

Formula

C10H17KNO9S2 • H2O

Formula Wt.

415.49

Solubility

Soluble in water

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

S3453 MSDS PDF

Info Sheet

S3453 Info Sheet PDF

References

Okulicz M. Multidirectional time-dependent effect of sinigrin and allyl isothiocyanate on metabolic parameters in rats. Plant Foods Hum Nutr. 2010 Sep;65(3):217-24. PMID: 20809411.

Washida K, Miyata M, Koyama T, et al. Suppressive effect of Yamato-mana (Brassica rapa L. Oleifera Group) constituent 3-butenyl glucosinolate (gluconapin) on postprandial hypertriglyceridemia in mice. Biosci Biotechnol Biochem. 2010;74(6):1286-9. PMID: 20530888.

Hwang ES, Lee HJ. Induction of quinone reductase by allylisothiocyanate (AITC) and the N-acetylcysteine conjugate of AITC in Hepa1c1c7 mouse hepatoma cells. Biofactors. 2006;26(1):7-15. PMID: 16614479

Hwang ES, Lee HJ. Allyl isothiocyanate and its N-acetylcysteine conjugate suppress metastasis via inhibition of invasion, migration, and matrix metalloproteinase-2/-9 activities in SK-Hep 1 human hepatoma cells. Exp Biol Med (Maywood). 2006 Apr;231(4):421-30. PMID: 16565438.

McWalter GK, Higgins LG, McLellan LI, et al. Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates. J Nutr. 2004 Dec;134(12 Suppl):3499S-3506S. PMID: 15570060.

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