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Formoterol Fumarate Dihydrate

Formoterol Fumarate Dihydrate

Product ID F5868
Cas No. 183814-30-4
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $142.80 In stock
10 mg $217.90 In stock
50 mg $736.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Formoterol is a long-acting β2-adrenergic receptor agonist that is clinically used to treat asthma and chronic obstructive pulmonary disease (COPD). Formoterol exhibits bronchodilatory, anti-asthma, and anti-obesity activities. In a clinical setting, formoterol increases resting energy expenditure, fat utilization, and mitochondrial biogenesis; it also increases mitochondrial expression of NADH dehydrogenase and ATP synthase.

Product Info

Cas No.

183814-30-4

Purity

≥98%

Formula

(C19H24N2O4)2 • C4H4O4 • 2H2O

Formula Wt.

840.91

Chemical Name

rel-N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4- methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]- formamide fumarate dihydrate

IUPAC Name

(E)-but-2-enedioic acid;N-[2-hydroxy-5-[(1S)-1-hydroxy-2-[[(2S)-1-(4-methoxyphenyl)propan- 2-yl]amino]ethyl]phenyl]formamide

Synonym

Formoterol Fumarate Dihydrate, Atock, Foradil, Oxeze

Melting Point

138-140°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

F5868 MSDS PDF

Info Sheet

F5868 Info Sheet PDF

References

Lee P, Day RO, Greenfield JR, et al. Formoterol, a highly β2-selective agonist, increases energy expenditure and fat utilisation in men. Int J Obes (Lond). 2013 Apr;37(4):593-7. PMID: 22641064.

Wills LP, Trager RE, Beeson GC, et al. The β2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis. J Pharmacol Exp Ther. 2012 Jul;342(1):106-18. PMID: 22490378.

Rider CF, King EM, Holden NS, et al. Inflammatory stimuli inhibit glucocorticoid-dependent transactivation in human pulmonary epithelial cells: rescue by long-acting beta2-adrenoceptor agonists. J Pharmacol Exp Ther. 2011 Sep;338(3):860-9. PMID: 21622733.

Custom Order

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