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Valacyclovir Hydrochloride

Product ID V0045
Cas No. 124832-27-5
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $74.10 In stock
100 mg $138.90 In stock
500 mg $509.20 In stock
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  • Product Info
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  • References
  • Description
  • Product Info
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  • Downloads
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Description

Valacyclovir is an antiviral compound that is clinically used to treat infection of the Varicella-zoster virus. This compound is a prodrug for acyclovir. Valacyclovir also inhibits neuraminidase and displays efficacy against other viruses such as herpes simplex virus and HIV-1.

Product Info

Cas No.

124832-27-5

Purity

≥98%

Formula

C13H20N6O4 • HCl

Formula Wt.

360.80

Chemical Name

L-Valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9- yl)methoxy]ethyl ester hydrochloride

IUPAC Name

2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate;hydrochloride

Synonym

Valacyclovir hydrochloride, BW-256U87

Melting Point

159-162°C

Solubility

Soluble in water (170 mg/mL), DMSO (14 mg/mL). Slightly soluble in ethanol (<1 mg/mL), methanol.

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

V0045 MSDS PDF

Info Sheet

V0045 Info Sheet PDF

References

Gupta D, Varghese Gupta S, Dahan A, et al. Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue. Mol Pharm. 2013 Feb 4;10(2):512-22. PMID: 23244438.

Roxby AC, Liu AY, Drake AL, et al. Short communication: T cell activation in HIV-1/herpes simplex virus-2-coinfected Kenyan women receiving valacyclovir. AIDS Res Hum Retroviruses. 2013 Jan;29(1):94-8. PMID: 22852760.

Andrei G, Snoeck R. Emerging drugs for varicella-zoster virus infections. Expert Opin Emerg Drugs. 2011 Sep;16(3):507-35. PMID: 21699441.

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