Description
Amikacin is an aminoglycoside antibiotic that exhibits antibacterial efficacy against gram negative bacteria. Amikacin binds the 30S ribosomal subunit, preventing translation.
Amikacin Disulfate
Product ID A5132
Cas No. 39831-55-5
Purity ≥98%
| Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 39831-55-5 |
|---|---|
| Purity | ≥98% |
| Formula | C22H43N5O13 • 2H2SO4 |
| Formula Wt. | 781.76 |
| Chemical Name | O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->6)-O- [6-amino-6-deoxy-α-D-glucopyranosyl-(1->4)]-N1- [(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D- streptamine sulfate |
| IUPAC Name | (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3, 5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S, 6R)-6-(aminomethyl)-3,4, 5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide; sulfuric acid |
| Synonym | Amikacin sulfate, Amikin, Biklin, Lukadin, Mikavir, Novamin, Pierami |
| Melting Point | 220-230°C(dec.) |
| Solubility | Soluble in water (50mg/mL). Insolulble in acetone and water. DMSO <1 mg/mL. |
| Appearance | White or Almost White Powder |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Barza M, Scheife RT. Drug therapy reviews: Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics--part 4: aminoglycosides. Am J Hosp Pharm. 1977 Jul;34(7):723-37. PMID: 407790.
Kawaguchi H. Discovery, chemistry, and activity of amikacin. J Infect Dis. 1976 Nov;134 SUPPL:S242-8. PMID: 825583.
King P, Citron DM, Griffith DC, et al. Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients. Diagn Microbiol Infect Dis. 2010 Feb;66(2):181-186. PMID: 19828274.