• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Capsaicin, natural

Capsaicin, natural

Product ID C0266
Cas No. 404-86-4
Purity ≥95%, capsaicinoids content
Product Unit SizeCostQuantityStock
100 mg $61.10 In stock
250 mg $85.90 In stock
1 g $255.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Capsaicin is an agonist of transient receptor potential vanilloid (TRPV) channels that was originally found in peppers of the Capsicum genus. Capsaicin exhibits analgesic, anti-inflammatory, anti-obesity, and anticancer chemotherapeutic activity. Capsaicin also displays bronchoconstrictive activity and is used as a natural irritant. In vivo, this compound desensitizes TRPV1 channels, inhibiting thermal and mechanical hyperalgesia. In other animal models, capsaicin inhibits adipogenesis, decreases metabolic dysregulation, activates PPARα, and suppresses weight gain and fat deposition. Capsaicin also induces apoptosis via ROS and disruption of the mitochondrial membrane and inhibits tumor growth in cellular and animal models of prostate cancer, breast cancer, pancreatic cancer, and hepatocellular carcinoma.

This mixture contains capsaicin, ≥65%, dihydrocapsaicin, ~20%, and nordihydrocapsaicin, ~4 %.

Product Info

Cas No.

404-86-4

Purity

≥95%, capsaicinoids content

Formula

C18H27NO3

Formula Wt.

305.41

Chemical Name

(6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8- methyl-6-nonenamide

IUPAC Name

(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide

Synonym

Axsain, Mioton, Zacin, Zostrix

Melting Point

65°C

Solubility

Soluble in ether, benzene, and chloroform. Practically insoluble in cold water.

Appearance

Slight yellowish-white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C0266 MSDS PDF

Info Sheet

C0266 Info Sheet PDF

Brochures

TRP Channel Modulator Flyer

References

Deng R, Yu S, Ruan X, et al. Capsaicin orchestrates metastasis in gastric cancer via modulating expression of TRPV1 channels and driving gut microbiota disorder. Cell Commun Signal. 2023 Dec 21;21(1):364. PMID: 38129926.

Díaz-Laviada I, Rodríguez-Henche N. The potential antitumor effects of capsaicin. Prog Drug Res. 2014;68:181-208. PMID: 24941670.

Leung FW. Capsaicin as an anti-obesity drug. Prog Drug Res. 2014;68:171-9. PMID: 24941669.

Kissin I. Vanilloid-induced conduction analgesia: selective, dose-dependent, long-lasting, with a low level of potential neurotoxicity. Anesth Analg. 2008 Jul;107(1):271-81. PMID: 18635498.

Jensen PG, Curtis PD, Dunn JA, et al. Field evaluation of capsaicin as a rodent aversion agent for poultry feed. Pest Manag Sci. 2003 Sep;59(9):1007-15. PMID: 12974352.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C1650

    β-Cembrenediol Methyl Ether

    Diterpene found in tobacco plants and cigarette...

    ≥98%
  • Q8133

    Quinacrine Dihydrochloride Dihydrate

    Cell membrane permeability modulator, topoisome...

    ≥97%
  • A9435

    Axitinib

    VEGFR inhibitor.

    ≥98%
  • L8011

    D-Luciferin Sodium

    Heterocyclic light-emitting compound, natural l...

    ≥99%
  • T4400

    TL-32711

    Smac mimetic; IAP inhibitor.

    ≥98%
  • R2713

    Recombinant HCV-NS4 Antigens

    Recombinant HCV antigen fragment.

    ≥95%
  • L3374

    Lisinopril Dihydrate

    Enalapril analog; ACE inhibitor.

    ≥98%
  • O486179

    Omeprazole Impurity C

    Impurity of omeprazole

    ≥99%
  • S3346

    Silodosin

    α1A-adrenergic antagonist.

    ≥98%
  • A0960

    Adrenocorticotropic Hormone (1-39), human

    Endogenous peptide hormone, involved in stress ...

    ≥95%
  • R5661

    Ropinirole Hydrochloride

    Indoline; D2/3 agonist.

    ≥99%
  • G4581

    Glucosamine Sulfate Potassium Chloride

    Endogenous amino acid sugar involved in cartila...

    ≥98%
  • D0006

    Dacomitinib Monohydrate

    EGFR inhibitor.

    ≥99%
  • R3475

    Risperidone

    Benzisoxazole; 5-HT7 and NMDA agonist, D-amino ...

    ≥98%
  • C5782

    Coumarin

    Benzopyrone found in various plants, precursor ...

    ≥98%
  • P1849

    Pemetrexed Disodium

    Thymidylate synthase inhibitor, potential SHMT,...

    ≥98%
  • E7376

    Estradiol

    Endogenous steroid hormone, involved in regulat...

    ≥97%
  • SB5776

    Snake venom – Bothrops alternatus (urutu)

    Snake venom found in Bothrops alternatus urutu....

    ≥98%
  • C5863

    Coptisine Chloride, natural

    Isoquinoline alkaloid found in a variety of pla...

    ≥98%
  • B5728

    Bohemine

    Purine derivative; CDK inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only