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Kanamycin A Monosulfate

Product ID K0053
Cas No. 25389-94-0
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $48.30 In stock
5 g $138.90 In stock
25 g $342.80 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Kanamycin A is an aminoglycoside antibiotic that binds the bacterial 16s rRNA subunit, inhibiting translocation and degrading target RNA; it displays antibacterial efficacy against gram negative bacteria. Kanamycin also prevents formation of the initiation complex. Kanamycin A also inhibits mammalian RNA splicing.

Product Info

Cas No.

25389-94-0

Purity

≥98%

Formula

C18H36N4O11 • H2SO4

Formula Wt.

582.58

Chemical Name

D-Streptamine,O-3-amino-3-deoxy-alpha-D- glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D- glucopyranosyl-(1-4))-2-deoxy-

IUPAC Name

(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S, 3R,4S,5S,6R)-4-amino-3, 5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane- 3,4,5-triol

Synonym

Kanamycin

Solubility

Soluble in water (100mM) or alcohol.

Appearance

White or Almost-White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

K0053 MSDS PDF

Info Sheet

K0053 Info Sheet PDF

References

Romanowska J, Reuter N, Trylska J. Comparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymes. Proteins. 2013 Jan;81(1):63-80. PMID: 22907688.

Patwardhan A, Cowan JA. Influence of charge and structure on the coordination chemistry of copper aminoglycosides. Dalton Trans. 2011 Feb 28;40(8):1795-801. PMID: 21218243.

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

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