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Vinorelbine Ditartrate

Product ID V3252
Cas No. 125317-39-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $59.50 In stock
5 mg $122.30 In stock
25 mg $424.80 In stock
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  • Product Info
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

Vinorelbine is a semi-synthetic vinca alkaloid originally found in Catharanthus that exhibits anticancer chemotherapeutic activity. Vinorelbine binds β-tubulin and stimulates microtubule depolymerization, acting as an anti-mitotic. Vinorelbine is clinically used to treat breast cancer and non-small cell lung cancer (NSCLC). In osteosarcoma cells, vinorelbine downregulates expression of cyclin D1 and upregulates expression of p53, inhibiting cell growth.

Product Info

Cas No.

125317-39-7

Purity

≥98%

Formula

C45H54N4O8 • 2C4H6O6

Formula Wt.

1079.10

Chemical Name

3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine ditartrate

Synonym

Eunades, Navelbine

Melting Point

219°C

Solubility

Soluble in water and ethanol.

Appearance

Off-white or light brown powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

V3252 MSDS PDF

Info Sheet

V3252 Info Sheet PDF

References

Capasso A. Vinorelbine in cancer therapy. Curr Drug Targets. 2012 Jul;13(8):1065-71. PMID: 22594474.

Roncuzzi L, Marti G, Baiocchi D, et al. Effect of Vinorelbine on cell growth and apoptosis induction in human osteosarcoma in vitro. Oncol Rep. 2006 Jan;15(1):73-7. PMID: 16328036.

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