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Pefloxacin Methanesulfonate Dihydrate

Product ID P1622
Cas No. 149676-40-4
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $50.00 In stock
25 g $150.00 In stock
100 g $275.00 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Pefloxacin is a synthetic third generation fluoroquinolone antibiotic. Pefloxacin displays antibacterial activity; it inhibits DNA gyrase and topoisomerase IV, suppressing DNA replication and transcription. Additionally, pefloxacin inhibits synthesis of penicillin-binding proteins, preventing bacterial cell wall formation. Pefloxacin exhibits moderate UV-induced phototoxicity.

Product Info

Cas No.

149676-40-4

Purity

≥98%

Formula

C17H20FN3O3 • CH3SO3H • 2H2O

Formula Wt.

465.50

Chemical Name

1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1- piperazinyl)-4-oxo-3-quinolinecarboxylic acid monomethanesulfonate

IUPAC Name

1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid

Synonym

Pefloxacine mesylate, Peflacine, Peflox

Appearance

Almost White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P1622 MSDS PDF

Info Sheet

P1622 Info Sheet PDF

References

Martínez LJ, Sik RH, Chignell CF. Fluoroquinolone antimicrobials: singlet oxygen, superoxide and phototoxicity. Photochem Photobiol. 1998 Apr;67(4):399-403. PMID: 9559584.

Grossato A, Fontana R. Synergy and mechanism of interaction between pefloxacin and penicillin G against enterococci. New Microbiol. 1997 Jul;20(3):221-5. PMID: 9258941.

Moreau NJ, Houot S, Joly-Guillou ML, et al. Characterisation of DNA gyrase and measurement of drug accumulation in clinical isolates of Acinetobacter baumannii resistant to fluoroquinolones. J Antimicrob Chemother. 1996 Dec;38(6):1079-83. PMID: 9023657.

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