Description
Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats.
Product Info
| Cas No. | 61413-54-5 |
|---|---|
| Purity | ≥98% |
| Formula | C16H21NO3 |
| Formula Wt. | 275.35 |
| IUPAC Name | 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone |
| Synonym | ZK62711 |
| Melting Point | 128-129°C |
| Solubility | Soluble in DMSO (warm 25mg/ml), ethanol (25 mg/ml warm). |
| Appearance | White to off-white powder |
Shipping and Storage
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
|---|---|
| Info Sheet |
References
Hu S, Cao Q, Xu P, et al. Rolipram stimulates angiogensis and attenuates neuronal apoptosis through the cAMP/cAMP-responsive element binding protein pathway following ischemic stroke in rats. Exp Ther Med. 2016 Mar; 11(3):1005-1010. PMID: 26998028.
Li YF, Huang Y, Amsdell S, et al. Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus. Neuropsychopharmacology. 2009 Oct; 34(11):2404-2419. PMID: 19516250.