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Rolipram

Product ID R5745
Cas No. 61413-54-5
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $107.30 In stock
25 mg $214.70 In stock
100 mg $686.90 Please Inquire
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  • Description
  • Product Info
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats.

Product Info

Cas No.

61413-54-5

Purity

≥98%

Formula

C16H21NO3

Formula Wt.

275.35

Chemical Name

4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one

IUPAC Name

4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone

Synonym

ZK62711, Rolipramum

Melting Point

128-129°C

Solubility

Soluble in DMSO (warm 25mg/ml), ethanol (25 mg/ml warm).

Appearance

White to off-white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R5745 MSDS PDF

Info Sheet

R5745 Info Sheet PDF

References

Hu S, Cao Q, Xu P, et al. Rolipram stimulates angiogensis and attenuates neuronal apoptosis through the cAMP/cAMP-responsive element binding protein pathway following ischemic stroke in rats. Exp Ther Med. 2016 Mar; 11(3):1005-1010. PMID: 26998028.

Li YF, Huang Y, Amsdell S, et al. Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus. Neuropsychopharmacology. 2009 Oct; 34(11):2404-2419. PMID: 19516250.

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