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Gallic Acid

Gallic Acid

Product ID G0145
Cas No. 149-91-7
Purity ≥98%
Product Unit SizeCostQuantityStock
10 g $42.80 In stock
100 g $63.70 In stock
500 g $153.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Gallic acid is a phenol found in various plants including sumac, oak, and witch hazel; it exhibits neuroprotective, antioxidative, anticancer, anti-metastatic, antibiotic, antacid, and anti-ulcerative activities. Gallic acid is commonly used as a standard for determining phenol content of analytes. Gallic acid scavenges ROS and displays benefit in animal models of cerebral ischemia/reperfusion. Gallic acid also induces Fas-mediated apoptosis in breast cancer cells and induces apoptosis and inhibits migration in osteosarcoma cells. This compound inhibits the production of α-hemolysin and cell adhesion in Staphylococcus. Additionally, gallic acid increases levels of glutathione peroxidase, glutathione, glutathione reductase, catalase, and superoxide dismutase and decreases levels of myeloperoxidase. In vivo, gallic acid decreases gastric acid secretion and ulcer formation.

Product Info

Cas No.

149-91-7

Purity

≥98%

Formula

C7H6O5

Formula Wt.

170.12

Chemical Name

3,4,5-Trihydroxybenzoic acid

IUPAC Name

3,4,5-trihydroxybenzoic acid

Synonym

3,4,5-Trihydroxybenzoic acid

Melting Point

235-240°C(dec.)

Solubility

Soluble in ethanol, acetone, DMSO, methanol. Slightly soluble in water (11.5 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

G0145 MSDS PDF

Info Sheet

G0145 Info Sheet PDF

References

Sun J, Li YZ, Ding YH, et al. Neuroprotective effects of gallic acid against hypoxia/reoxygenation-induced mitochondrial dysfunctions in vitro and cerebral ischemia/reperfusion injury in vivo. Brain Res. 2014 Sep 22. [Epub ahead of print]. PMID: 25251593.

Wang K, Zhu X, Zhang K, et al. Investigation of gallic Acid induced anticancer effect in human breast carcinoma mcf-7 cells. J Biochem Mol Toxicol. 2014 Sep;28(9):387-93. PMID: 24864015.

Luís Â, Silva F, Sousa S, et al. Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids. Biofouling. 2014 Jan;30(1):69-79. PMID: 24228999.

Liang W, Li X, Li Y, et al. Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells. Int J Oncol. 2014 Jan;44(1):91-8. PMID: 24173143.

Sen S, Asokkumar K, Umamaheswari M, et al. Antiulcerogenic effect of gallic Acid in rats and its effect on oxidant and antioxidant parameters in stomach tissue. Indian J Pharm Sci. 2013 Mar;75(2):149-55. PMID: 24019562.

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