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Nifedipine

Product ID N3228
Cas No. 21829-25-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $61.50 In stock
5 g $143.10 In stock
25 g $278.20 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
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  • Downloads
  • References
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Description

Nifedipine is a dihydropyridine that acts as an antagonist at L-type Ca2+ channels. Nifedipine exhibits antihypertensive, anti-anginal, cardioprotective, tocolytic, and analgesic activities. This compound is clinically used in the treatment of angina and to prevent preterm labor in pregnant females. Additionally, nifedipine alters pain thresholds in the tail withdrawal electric stimulation test.

Product Info

Cas No.

21829-25-4

Purity

≥98%

Formula

C17H18N2O6

Formula Wt.

346.33

Chemical Name

1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5- pyridinedicarboxylic acid dimethyl ester

IUPAC Name

dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Synonym

Adalat, Anifed, Aprical, Cordipin, Corotrend, Fenihidine, Nifedicor, Nifensar, Orix, Procardia, Sepamit, Zenusin

Melting Point

172-174°C

Solubility

Soluble in DMSO, acetone (100 mg/mL) or ethanol. Insoluble in water.

Appearance

Yellow crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

N3228 MSDS PDF

Info Sheet

N3228 Info Sheet PDF

References

Gáspár R, Hajagos-Tóth J. Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations. Pharmaceuticals (Basel). 2013 May 23;6(6):689-99. PMID: 24276256.

Martín MI, del Val VL, Colado MI, et al. Behavioral and analgesic effects induced by administration of nifedipine and nimodipine. Pharmacol Biochem Behav. 1996 Sep;55(1):93-8. PMID: 8870043.

Zsotér TT, Church JG. Calcium antagonists. Pharmacodynamic effects and mechanism of action. Drugs. 1983 Feb;25(2):93-112. PMID: 6131809.

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