Carvedilol

Name: Carvedilol
SKU: C0365
Availability: InStock

Product ID C0365

Cas No. 72956-09-3

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Carvedilol is an α1- and β1/2-adrenergic receptor antagonist used to treat congestive heart failure; its inhibitory action at adrenergic receptors slows heart rhythm, decreasing force, pressure, and cardiac workload. Carvedilol also inhibits release of pro-inflammatory cytokines TNF-α and IL-6 and production of eicosanoids PGE2 and LTB4, alleviating oxidative stress and indicating antioxidative and anti-arthritic activities. Additionally, this compound may exhibit anti-atherosclerotic and anti-diabetic activity through its inhibition of acid sphingomyelinase (FIASMA).

Product Info

Cas No.	72956-09-3
Purity	≥98%
Formula	C₂₄H₂₆N₂O₄
Formula Wt.	406.47
Chemical Name	1-(99H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
IUPAC Name	1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
Synonym	Coreg, Dimitone, Eucardic, Kredex, Querto
Melting Point	114-115°C
Solubility	Soluble in DMSO (>20 mg/mL), and methylene chloride. Sparingly soluble in ethanol(4 mg/mL), isopropanol and ethyl ether. Insoluble in water (0.02 mg/mL).
Appearance	White to off white crystalline powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	C0365 MSDS PDF
Info Sheet	C0365 Info Sheet PDF

References

Arab HH, El-Sawalhi MM. Carvedilol alleviates adjuvant-induced arthritis and subcutaneous air pouch edema: modulation of oxidative stress and inflammatory mediators. Toxicol Appl Pharmacol. 2013 Apr 15;268(2):241-8. PMID: 23360886.

Kornhuber J, Muehlbacher M, Trapp S, et al. Identification of novel functional inhibitors of acid sphingomyelinase. PLoS One. 2011;6(8):e23852. PMID: 21909365.

Stafylas PC, Sarafidis PA. Carvedilol in hypertension treatment. Vasc Health Risk Manag. 2008;4(1):23-30. PMID: 18629377.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Name
This field is for validation purposes and should be left unchanged.

Carvedilol

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

5-Fluorocytosine

Icilin

Glucagon, human

Chlorzoxazone

S-(−)-Sulpiride

Tigecycline

AHU-377 Tris Salt

Phleomycin

Rofecoxib

Alyssin

7-Aminoactinomycin D

Latrunculin A

GSK-1070916

Gastric Inhibitory Peptide, human

Nigericin Sodium

S-(N-Methylsulfinylbutylthiocarbamoyl)-glutathione

Bosutinib, structural isomer

LY-404187

Butoconazole Nitrate

Aristolochic Acid A

Footer