Description
Jasplakinolide is a marine toxin that stabilizes actin by inducing polymerization and preventing depolymerization and is used in research models. In animal models, jasplakinolide stimulates follicule growth.
Jasplakinolide
Product ID J0274
Cas No. 102396-24-7
Purity ≥98%
| Unit Size | Cost | Quantity | Stock |
|---|
Product Info
| Cas No. | 102396-24-7 |
|---|---|
| Purity | ≥98% |
| Formula | C36H45BrN4O6 |
| Formula Wt. | 709.68 |
| Chemical Name | (4R,7R,10S,13S,15E,17R,19S)-7-[(2-Bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone |
| IUPAC Name | (4R,7R,10S,13S,15E,17R,19S)-7-[(2-Bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone |
| Synonym | Jaspamide |
| Solubility | Soluble in ethanol, methanol or DMSO. |
| Appearance | Off-white solid. |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
|---|---|
| Info Sheet |
References
Aida N, Ushikubo T, Kobayashi F, et al. Actin stabilization induces apoptosis in cultured porcine epithelial cell rests of Malassez. Int Endod J. 2015 Jun 27. [Epub ahead of print]. PMID: 26118334.
Cheng Y, Feng Y, Jansson L, et al. Actin polymerization-enhancing drugs promote ovarian follicle growth mediated by the Hippo signaling effector YAP. FASEB J. 2015 Jun;29(6):2423-30. PMID: 25690654.
Schwingshackl A, Roan E, Teng B, et al. TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements. PLoS One. 2015 May 22;10(5):e0126781. PMID: 26001192.