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Jasplakinolide

Product ID J0274
Cas No. 102396-24-7
Purity ≥98%
Product Unit SizeCostQuantityStock
50 µg $407.20 Please Inquire
100 µg $750.10 Please Inquire
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Jasplakinolide is a marine toxin that stabilizes actin by inducing polymerization and preventing depolymerization and is used in research models. In animal models, jasplakinolide stimulates follicule growth.

Product Info

Cas No.

102396-24-7

Purity

≥98%

Formula

C36H45BrN4O6

Formula Wt.

709.68

Chemical Name

(4R,7R,10S,13S,15E,17R,19S)-7-[(2-Bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone

IUPAC Name

(4R,7R,10S,13S,15E,17R,19S)-7-[(2-Bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone

Synonym

Jaspamide

Solubility

Soluble in ethanol, methanol or DMSO.

Appearance

Off-white solid.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

J0274 MSDS PDF

Info Sheet

J0274 Info Sheet PDF

References

Aida N, Ushikubo T, Kobayashi F, et al. Actin stabilization induces apoptosis in cultured porcine epithelial cell rests of Malassez. Int Endod J. 2015 Jun 27. [Epub ahead of print]. PMID: 26118334.

Cheng Y, Feng Y, Jansson L, et al. Actin polymerization-enhancing drugs promote ovarian follicle growth mediated by the Hippo signaling effector YAP. FASEB J. 2015 Jun;29(6):2423-30. PMID: 25690654.

Schwingshackl A, Roan E, Teng B, et al. TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements. PLoS One. 2015 May 22;10(5):e0126781. PMID: 26001192.

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