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AM630

AM630

Product ID A480010
Cas No. 164178-33-0
Purity ≥97%
Product Unit SizeCostQuantityStock
5 mg $64.50 In stock
25 mg $226.10 In stock
100 mg $679.70 In stock
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Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AM630 is a CB2 receptor antagonist. It is selective for CB2 over the CB1 receptor. AM630 activates TRPA1 in sensory neurons. This activation increases the hyperalgesic effect from capsaicin-induced pain models.

Product Info

Cas No.

164178-33-0

Purity

≥97%

Formula

C23H25IN2O3

Formula Wt.

504.37

Chemical Name

6-Iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)methanone

IUPAC Name

[6-iodo-2-methyl-1-(2-morpholin-4-ylethyl)indol-3-yl]-(4-methoxyphenyl)methanone

Synonym

AM 630, Iodopravadoline

Solubility

100mM in DMSO

Appearance

White to off-white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A480010 MSDS PDF

Info Sheet

A480010 Info Sheet PDF

References

Ross RA, Brockie HC, Stevenson LA, et al. Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656 and AM630. Br J Pharmacol. 1999 Feb;126(3):665-72. PMID: 10188977

Patil M, Patwardhan A, Salas MM, et al. Cannabinoid receptor antagonists AM251 and AM630 activate TRPA1 in sensory neurons. Neuropharmacology, 2011 Sep;61(4):778-88. PMID: 21645531.

Custom Order

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