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Rigin

Product ID R3224
Cas No. 77727-17-4
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $89.20 In stock
10 mg $151.30 In stock
25 mg $267.20 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Rigin is a tuftsin-like tetrapeptide with the sequence G-Q-P-R that is derived from IgG. Rigin exhibits immunomodulatory activity, stimulating phagocytosis, activating polymorphonuclear lymphocytes and macrophages, and protecting against stress-induced damage.

Product Info

Cas No.

77727-17-4

Purity

≥95%

Formula

C18H32N8O6

Formula Wt.

456.51

IUPAC Name

(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[(2-aminoacetyl)amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid

Synonym

G-Q-P-R, GQPR

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

R3224 Info Sheet PDF

References

Dutta RC, Puri A, Anand N. Immunomodulatory potential of hydrophobic analogs of Rigin and their role in providing protection against Plasmodium berghei infection in mice. Int Immunopharmacol. 2001 May;1(5):843-55. PMID: 11379040.

Klusha VE, Mutsenietse RK, Svirskis ShV, et al. Neuroimmunoregulatory properties of short protein fragments in rats exposed to immobilization stress. Biull Eksp Biol Med. 1987 Aug;104(8):186-7. PMID: 2887222.

Veretennikova NI, Chipens GI, Nikiforovich GV, et al. Rigin, another phagocytosis-stimulating tetrapeptide isolated from human IgG. Confirmations of a hypothesis. Int J Pept Protein Res. 1981 Apr;17(4):430-5. PMID: 7309346.

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