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Glucosamine Hydrochloride

Product ID G4580
Cas No. 66-84-2
Purity ≥96%
Product Unit SizeCostQuantityStock
25 g $31.90 In stock
100 g $63.20 In stock
500 g $245.60 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Glucosamine is an endogenous amino sugar precursor to glycosylated protein and lipid formation; it is used in the making of cartilage. Glucosamine improves joint function and is often found in dietary supplements. Glucosamine exhibits anticancer and anti-fibrotic activities. In prostate cancer cells, glucosamine decreases N-glycosylation of gp130, suppressing binding of IL-6, phosphorylation of JAK2, SHP2, and STAT3, and cellular proliferation. Additionally, glucosamine decreases TGF-β1-induced expression of collagen I, fibronectin, and αSMA, inhibits phosphorylation of Smad2/3, and suppresses the development of renal fibrosis in vivo.

Product Info

Cas No.

66-84-2

Purity

≥96%

Formula

C6H13NO5 • HCl

Formula Wt.

215.6

Chemical Name

2-Amino-2-deoxy-D-glucose hydrochloride

IUPAC Name

(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol;hydrochloride

Synonym

D-Glucosamine HCl,2-Amino-2-deoxy-D-glucopyranose hydrochloride, Chitosamine hydrochloride

Melting Point

190-194°C

Solubility

Soluble in water.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

G4580 MSDS PDF

Info Sheet

G4580 Info Sheet PDF

References

Chesnokov V, Gong B, Sun C, et al. Anti-cancer activity of glucosamine through inhibition of N-linked glycosylation. Cancer Cell Int. 2014 May 28;14:45. PMID: 24932134.

Park J, Lee SY, Ooshima A, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84. PMID: 24072041.

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