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Amygdalin

Product ID A5193
Cas No. 29883-15-6
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $57.20 In stock
5 g $85.90 In stock
25 g $343.50 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

Amygdalin is a glucoside found in stone fruits and apples that exhibits antinociceptive, analgesic, and anticancer chemotherapeutic activities. In animal models, amygdalin decreases formalin-induced pain. Amygdalin inhibits viability of leukemia cells and induces apoptosis in prostate cancer cells, increasing levels of Bax and decreasing levels of Bcl-2; in vivo, amygdalin induces apoptosis and inhibits tumor xenograft growth.

Product Info

Cas No.

29883-15-6

Purity

≥98%

Formula

C20H27NO11

Formula Wt.

457.43

Chemical Name

[(6-O-β-D-glucopyranosyl-beta-D-gluco-pyranosyl- β-D-gluco-pyranosyl)oxy]-benzeneacetonitrile

IUPAC Name

2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] oxyacetonitrile

Synonym

Amygdaloside

Melting Point

210ªC-215°C

Solubility

Soluble in hot water (0.1g/mL) or alcohol (1g/900mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A5193 MSDS PDF

Info Sheet

A5193 Info Sheet PDF

References

Chen Y, Ma J, Wang F, et al. Amygdalin induces apoptosis in human cervical cancer cell line HeLa cells. Immunopharmacol Immunotoxicol. 2013 Feb;35(1):43-51. PMID: 23137229.

Hwang HJ, Kim P, Kim CJ, et al. Antinociceptive effect of amygdalin isolated from Prunus armeniaca on formalin-induced pain in rats. Biol Pharm Bull. 2008 Aug;31(8):1559-64. PMID: 18670089.

Chang HK, Shin MS, Yang HY, et al. Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells. Biol Pharm Bull. 2006 Aug;29(8):1597-602. PMID: 16880611.

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