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Telbivudine

Telbivudine

Product ID T1844
Cas No. 3424-98-4
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $84.30 In stock
25 mg $149.70 In stock
100 mg $377.70 In stock
250 mg $679.10 In stock
1 g $1,795.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Telbivudine is an antiviral and immunomodulatory compound that is commonly used to treat chronic hepatitis B infections. Telbivudine is the L-isomer of thymidine and acts as a nucleoside analog. Clinically, telbivudine increases expression of CD127 on CD8+ memory T cells; this compound also decreases hepatitis B viral DNA and normalizes levels of alanine aminotransferase.

Product Info

Cas No.

3424-98-4

Purity

≥98%

Formula

C10H14N2O5

Formula Wt.

242.23

IUPAC Name

1-[(2S,4R, 5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Synonym

Epavudine, L-Thymidine, 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil β-L-2-deoxythymidine β-L-thymidine (LdT) 1-[(2S,4R,5S)-4-hydroxy-5-hydroxymethyltetrahydrofuran-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T1844 MSDS PDF

Info Sheet

T1844 Info Sheet PDF

References

Nan XP, Zhang Y, Yu HT, et al. Inhibition of viral replication downregulates CD4(+)CD25(high) regulatory T cells and programmed death-ligand 1 in chronic hepatitis B. Viral Immunol. 2012 Feb;25(1):21-8. PMID: 22233255.

Lv G, Ying L, Ma WJ, et al. Dynamic analysis of CD127 expression on memory CD8 T cells from patients with chronic hepatitis B during telbivudine treatment. Virol J. 2010 Aug 31;7:207. PMID: 20807412.

Lai CL, Leung N, Teo EK, et al. A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B. Gastroenterology. 2005 Aug;129(2):528-36. PMID: 16083710.

Custom Order

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