• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
GDC-0152 Free Base

GDC-0152 Free Base

Product ID G124086
Cas No. 873652-48-3
Purity ≥96%
Product Unit SizeCostQuantityStock
1 mg $58.50 In stock
5 mg $194.70 In stock
25 mg $369.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

GDC-0152 is an X-linked inhibitor of apoptosis protein (XIAP). GDC-0152 induces apoptosis in several cell lines including HL-60, NB4, osteosarcoma, glioblastomas among others.

Product Info

Cas No.

873652-48-3

Purity

≥96%

Formula

C25H34N6O3S

Formula Wt.

498.65

Chemical Name

N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-L-prolinamide

IUPAC Name

N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-L-prolinamide

Synonym

GDC0152, GDC 0152

Solubility

DMSO

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G124086 MSDS PDF

Info Sheet

G124086 Info Sheet PDF

References

Liang, P, Hu, R, Dong, HM, et al. GDC-0152-induced autophagy promotes apoptosis in HL-60 cells. Mol Cell Biochem 445:135-143 (2018). PMID:29299747 DOI:10.1007/s11010-017-3258-7.

Yang, L, Shu T, Liang, Y, et al GDC-0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2bia PI3K/AKT but not p38MAPK signaling pathway. Int J Oncol. 46:1651-8 (2015). PMID:25651778.

Shekhar, TM, Burvenich, IJG, HARRIS, M., ET AL SMAC MIMETICS LCL161 AND GDC-0152 INHIBIT OSTEOSARCOMA GROWTH AND METASTAsis IN MICE. BMC Cancer 19:924 (2019). PMID:31521127

Dizdar, L, Junemann LM, Werner TA., et al. Clinicopathological and functional implications of the inhibitor of apoptosis proteins survivin and XIAP in esophageal cancer Oncol Lett 15:3779-3789 (2018) PMID: 2946 7895

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S3476

    Sitagliptin Phosphate Monohydrate

    DPP4 inhibitor.

    ≥98%
  • D183744

    Destruxin A

    Cyclic depsipeptide is a secondary metabolite i...

    ≥98%
  • B807214

    Buflomedil Hydrochloride

    Alpha blocker and vasoactive agent.

    ≥99%
  • O783743

    OTSSP167 Hydrochloride

    MELK inhibitor.

    ≥98%
  • T1002

    2-Debenzoyl Paclitaxel-2-(2-Methyl-2-Butenoate)

    Synthesis intermediate

    ≥95%
  • D3301

    Diaveridine

    Coccidiostat; dihydrofolate reductase inhibitor...

    ≥98%
  • T2800

    Thalidomide

    Immunomodulator; teratogen.

    ≥98%
  • U6857

    Urodilatin CCC

    ANP fragment, natriuretic peptide; Na+/K+ ATPas...

    ≥98%
  • E6376

    Eptifibatide

    Glycoprotein IIb/IIIa inhibitor.

    ≥98%
  • G5320

    GNF-2

    Abl inhibitor.

    ≥98%
  • K0117

    Kaempferol

    Flavonol found in various plant sources.

    ≥98%
  • D0025

    DAMGO

    Synthetic peptice; μOR agonist.

    ≥95%
  • P7608

    PTC124

    Read-through agent and nonsense mutation target...

    ≥98%
  • K9858

    Kyotorphin

    Opioid neuropeptide; kyotorphin agonist.

    ≥95%
  • R183731

    Resiquimod

    Toll-like receptor 7/8 agonist

    ≥98%
  • P333400

    PIK-75

    p110α inhibitor.

    ≥99%
  • T342710

    Tirzepatide

    GLP-1/GIP receptor co-agonist

    ≥98%
  • C0250

    Calcitonin Gene Related Peptide II, human

    Calcitonin-family peptide, involved in vasodila...

    ≥95%
  • P9671

    Pyrazinamide

    Nicotinamide analog prodrug; fatty acid synthet...

    ≥98%
  • N0069

    Naringin

    Flavanone glycoside found in citrus fruit; SERM...

    ≥97%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only