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Zearalenone

Product ID Z1602
Cas No. 17924-92-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $43.50 In stock
5 mg $86.30 In stock
10 mg $154.80 In stock
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  • Description
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Description

Zearalenone is a non-steroid mycotoxin initially produced by species of Fusarium that occurs as a contaminant in grain products such as cereal. Zearalenone exhibits estrogenic effects, activating estrogen receptors. In vivo, zearalenone causes hormonal effects and abnormal reproductive development. In male germ cells such as spermatocytes and spermatogonia, zearalenone induces apoptosis. In other in vitro models, this compound induces oxidative stress and cytotoxicity, altering levels of glutathione, TBARS, and HSP70.

Product Info

Cas No.

17924-92-4

Purity

≥98%

Formula

C18H22O5

Formula Wt.

318.36

IUPAC Name

(2E,11S)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14), 2,15,17-tetraene-7,13-dione

Melting Point

159-163°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

Z1602 MSDS PDF

Info Sheet

Z1602 Info Sheet PDF

References

Lee H, Kang C, Yoo YS, et al. Cytotoxicity and the induction of the stress protein Hsp 70 in Chang liver cells in response to zearalenone-induced oxidative stress. Environ Toxicol Pharmacol. 2013 Sep;36(2):732-40. PMID: 23917164.

Prouillac C, Koraichi F, Videmann B, et al. In vitro toxicological effects of estrogenic mycotoxins on human placental cells: structure activity relationships. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):366-75. PMID: 22310176.

Kim IH, Son HY, Cho SW, et al. Zearalenone induces male germ cell apoptosis in rats. Toxicol Lett. 2003 Mar 3;138(3):185-92. PMID: 12565195.

Boyd PA, Wittliff JL. Mechanism of Fusarium mycotoxin action in mammary gland. J Toxicol Environ Health. 1978 Jan;4(1):1-8. PMID: 633402.

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