Description
MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells.
Product Info
| Cas No. | 1072833-77-2 |
|---|---|
| Purity | ≥98% |
| Formula | C14H19BCl2N2O4 |
| Formula Wt. | 361.03 |
| IUPAC Name | [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid |
| Synonym | Ixazomib |
| Solubility | DMSO 72 mg/mL (199.42 mM) Ethanol 9 mg/mL (24.92 mM) Water Insoluble |
| Appearance | White Powder |
Shipping and Storage
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
|---|---|
| Info Sheet |
References
Tian Z, Zhao JJ, Tai YT, et al. Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells. Blood. 2012 Nov 8;120(19):3958-67. PMID: 22983447.