Name: MLN-2238
SKU: M4455
Availability: InStock

Description

MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells.

Product Info

Cas No.	1072833-77-2
Purity	≥95%
Formula	C₁₄H₁₉BCl₂N₂O₄
Formula Wt.	361.03
IUPAC Name	[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
Synonym	Ixazomib
Solubility	DMSO 72 mg/mL (199.42 mM) Ethanol 9 mg/mL (24.92 mM) Water Insoluble
Appearance	White Powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	M4455 MSDS PDF
Info Sheet	M4455 Info Sheet PDF

References

Tian Z, Zhao JJ, Tai YT, et al. Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells. Blood. 2012 Nov 8;120(19):3958-67. PMID: 22983447.

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MLN-2238

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