Description
MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells.
| Cas No. | 1072833-77-2 |
|---|---|
| Purity | ≥95% |
| Formula | C14H19BCl2N2O4 |
| Formula Wt. | 361.03 |
| IUPAC Name | [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid |
| Synonym | Ixazomib |
| Solubility | DMSO 72 mg/mL (199.42 mM) Ethanol 9 mg/mL (24.92 mM) Water Insoluble |
| Appearance | White Powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Tian Z, Zhao JJ, Tai YT, et al. Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells. Blood. 2012 Nov 8;120(19):3958-67. PMID: 22983447.
CB2 receptor antagonist.
AT1 inhibitor.
Zika Virus antigen
Synthetic catechol; ER agonist, microtubule pol...
Iron chelator.
Synthetic ITC.
Histamine H1 antagonist.
MEK1/2 and Raf inhibitor.
CB1 receptor antagonist/ inverse agonist.
PDEδ inhibitor.
Synthetic steroid hormone; AR agonist, ER and P...
Steroidal saponin found in Dioscorea.
Glucosinolate found in cruciferous vegetables.<...
α1-adrenergic antagonist.
Vitamin D2, ergocalciferol metabolite; VDR agon...
Endogenous sulfonic acid involved in Ca2+ signa...
Mycotoxin contaminant found in cereal grains.
Mineralocorticoid, aldosterone, AR antagonist, ...
beta-catenin inhibitor
p38 MAPK inhibitor.