| Product Unit Size | Cost | Quantity | Stock |
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Ebastine is a second-generation antihistamine and anti-inflammatory compound that is clinically used to treat allergic rhinitis. Like other newer antihistamines, administration of ebastine results in less of a sedative effect than early antihistamines. Ebastine also increases production of IFN-γ. This compound acts as an antagonist at histamine H1 receptors.
| Cas No. | 90729-43-4 |
|---|---|
| Purity | ≥98% |
| Formula | C32H39NO2 |
| Formula Wt. | 469.66 |
| IUPAC Name | 4-(4-benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one |
| Melting Point | 80-86°C |
| Appearance | White to Off-White Fine Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Ciprandi G. Clinical utility and patient adherence with ebastine for allergic rhinitis. Patient Prefer Adherence. 2010 Oct 14;4:389-95. PMID: 21206514.
Ciprandi G, Cirillo I, Pistorio A, et al. Ebastine increases IFN-gamma production in patients with persistent allergic rhinitis. J Biol Regul Homeost Agents. 2009 Jan-Mar;23(1):31-6. PMID: 19321044.
Tagawa M, Kano M, Okamura N, et al. Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine. Br J Clin Pharmacol. 2001 Nov;52(5):501-9. PMID: 11736858.
