Description
Tamsulosin is an α1-adrenergic receptor antagonist that is clinically used to treat benign prostatic hyperplasia (BPH). Tamsulosin inhibits peristaltic activity, increases bladder blood flow, and decreases bladder overactivity.
Product Unit Size | Cost | Quantity | Stock |
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Tamsulosin is an α1-adrenergic receptor antagonist that is clinically used to treat benign prostatic hyperplasia (BPH). Tamsulosin inhibits peristaltic activity, increases bladder blood flow, and decreases bladder overactivity.
Cas No. | 106463-17-6 |
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Purity | ≥98% |
Formula | C20H28N2O5S • HCl |
Formula Wt. | 444.98 |
Chemical Name | 5-[(2R)-2-[[2-(2-Ethoxy-phenoxy)-ethyl]]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride |
IUPAC Name | 5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2- methoxybenzenesulfonamide;hydrochloride |
Synonym | Flomax, Harnal, Pradif |
Melting Point | 228-230°C |
Solubility | Slightly soluble in water to 10 mM. Weakly soluble in methanol. DMSO to 100 mM. |
Appearance | White Powder |
Store Temp | 4°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Okutsu H, Matsumoto S, Ohtake A, et al. Effect of tamsulosin on bladder blood flow and bladder function in a rat model of bladder over distention/emptying induced bladder overactivity. J Urol. 2011 Dec;186(6):2470-7. PMID: 22019173.
Barkin J. Review of dutasteride/tamsulosin fixed-dose combination for the treatment of benign prostatic hyperplasia: efficacy, safety, and patient acceptability. Patient Prefer Adherence. 2011;5:483-90. PMID: 22003286.
Rajpathy J, Aswathaman K, Sinha M, et al. An in vitro study on human ureteric smooth muscle with the alpha1-adrenoceptor subtype blocker, tamsulosin. BJU Int. 2008 Dec;102(11):1743-5. PMID: 18778345.
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