LKT Labs

Biochemicals for Life Science Research

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Snake venom – Crotalus durissus terrificus

Product ID SC7056
Cas No.
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $175.10 In stock
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Description

This product is a snake venom found in Crotalus durrisus terrificus including several toxins that cause myalgia, muscle weakness, and rhabdomyolysis. Crotoxin acts on N-type and P/Q-type Ca2+ channels to induce glutamate release and crotamine induces acetylcholine (ACh) and DA release. Crotoxin also potentiates activity at L-type Ca2+ channels. Gyrotoxin is a serine protease with thrombin-like activity. Together, these toxins may induce paralysis, acting as a neuromuscular junction (NMJ) blocker.

Product Info

Purity

≥98%

Appearance

Yellow Crystalline Solid

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

SC7056 MSDS PDF

Info Sheet

SC7056 Info Sheet PDF

References

Bucaretchi F, De Capitani EM, Hyslop S, et al. Compartment syndrome after South American rattlesnake (Crotalus durissus terrificus) envenomation. Clin Toxicol (Phila). 2014 Jul;52(6):639-41. PMID: 24940645.

Vargas LS, Lara MV, Gonçalves R, et al. The intrahippocampal infusion of crotamine from Crotalus durissus terrificus venom enhances memory persistence in rats. Toxicon. 2014 Jul;85:52-8. PMID: 24813333.

Lomeo Rda S, Gonçalves AP, Silva CN, et al. Crotoxin from Crotalus durissus terrificus snake venom induces the release of glutamate from cerebrocortical synaptosomes via N and P/Q calcium channels. Toxicon. 2014 Jul;85:5-16. PMID: 24751366.

Yonamine CM, Kondo MY, Nering MB, et al. Enzyme specificity and effects of gyroxin, a serine protease from the venom of the South American rattlesnake Crotalus durissus terrificus, on protease-activated receptors. Toxicon. 2014 Mar;79:64-71. PMID: 24412460.

Ribeiro Gde B, Almeida HC, Velarde DT, et al. Study of crotoxin on the induction of paralysis in extraocular muscle in animal model. Arq Bras Oftalmol. 2012 Oct;75(5):307-12. PMID: 23471322.

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