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Repaglinide

Product ID R1860
Cas No. 135062-02-1
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $166.10 In stock
250 mg $319.50 In stock
1 g $1,022.30 In stock
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  • Description
  • Product Info
  • Shipping and Storage
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Repaglinide is a derivative of meglitinide that non-selectively binds the sulfonylurea subunit of ATP-sensitive K+ channels, inducing channel closure. Repaglinide is a fast acting anti-diabetic compound that increases insulin release.

Product Info

Cas No.

135062-02-1

Purity

≥98%

Formula

C27H36N2O4

Formula Wt.

452.59

Chemical Name

2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid

IUPAC Name

2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2- oxoethyl]benzoic acid

Melting Point

130-131°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R1860 MSDS PDF

Info Sheet

R1860 Info Sheet PDF

References

Zünkler BJ. Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects. Pharmacol Ther. 2006 Oct;112(1):12-37. PMID: 16647758.

Proks P, Reimann F, Green N, et al. Sulfonylurea stimulation of insulin secretion. Diabetes. 2002 Dec;51 Suppl 3:S368-76. PMID: 12475777.

Hatorp V. Clinical pharmacokinetics and pharmacodynamics of repaglinide. Clin Pharmacokinet. 2002;41(7):471-83. PMID: 12083976.

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