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M2698

M2698

Product ID M002698
Cas No. 1379545-95-5
Purity ≥99%
Product Unit SizeCostQuantityStock
1 mg $115.90 In stock
5 mg $286.10 In stock
25 mg $729.10 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

M2698 is a dual inhibitor of p70S6K and Akt. In cancers with dysregulation of the PI3K/Akt/mTOR signaling pathway, M2698 demonstrates tumor growth inhibition, such as in mouse xeongraft models of triple-negative and Her-2 expressing breast cancer cell lines.

Product Info

Cas No.

1379545-95-5

Purity

≥99%

Formula

C21H19ClF3N5O

Formula Wt.

449.86

Chemical Name

4-[[(1S)-2-(azetidin-1-yl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl]amino]quinazoline-8-carboxamide

IUPAC Name

4-({(1S)-2-(1-Azetidinyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl}amino)-8-quinazolinecarboxamide

Synonym

M 2698, M-2698, MSC-2363318A

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

M002698 MSDS PDF

Info Sheet

M002698 Info Sheet PDF

References

Machl A., Wilker E., et al. M2698 is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier. Am J Cancer Res. 6(4):806-18 (2016).

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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