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Fumitremorgin C

Fumitremorgin C

Product ID F8250
Cas No. 118974-02-0
Purity ≥98%
Product Unit SizeCostQuantityStock
250 µg $156.80 In stock
1 mg $456.50 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Fumitremorgin C is a mycotoxin found in Aspergillus and Penicillum that inhibits ATP-binding cassette G2 (ABC-G2), a protein associated with multidrug resistance. Fumitremorgin C inhibits proliferation and viability of kidney side population cells.

Product Info

Cas No.

118974-02-0

Purity

≥98%

Formula

C22H25N3O3

Formula Wt.

379.46

Chemical Name

(5aS,12S,14aS)-9-Methoxy-12-(2-methyl-1-propen-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione

IUPAC Name

(5aS,12S,14aS)-9-Methoxy-12-(2-methyl-1-propen-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione

Solubility

Soluble in DMSO, methanol, acetone, DMF or chloroform.

Appearance

White to light brown powder.

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

F8250 MSDS PDF

Info Sheet

F8250 Info Sheet PDF

References

Dame ZT, Suwannarach N, Lumyong S, et al. A new citrinin dimer isolated from Aspergillus terreus strain ZDF21. Nat Prod Commun. 2015 Apr;10(4):623-4. PMID: 25973492.

Xie J, Jin B, Li DW, et al. ABCG2 regulated by MAPK pathways is associated with cancer progression in laryngeal squamous cell carcinoma. Am J Cancer Res. 2014 Nov 19;4(6):698-709. PMID: 25520861.

Liu HB, Meng QH, Du DW, et al. The effects of ABCG2 on the viability, proliferation and paracrine actions of kidney side population cells under oxygen-glucose deprivation. Int J Med Sci. 2014 Jul 20;11(10):1001-8. PMID: 25076846.

Custom Order

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