Name: TMS
SKU: T503720
Availability: InStock

Description

TMS is a selective inhibitor of cytochrome P450 1B1 (CYP1B1), an enzyme which metabolizes endogenous and exogenous xenobiotics. It is 50-fold selective over CYP1A1 and more than 500-fold selective over CYP1A2.

Product Info

Cas No.	24144-92-1
Purity	≥99%
Formula	C₁₈H₂₀O₄
Formula Wt.	300.35
Chemical Name	(E)-1-(3,5-Dimethoxystyryl)-2,4-dimethoxybenzene
IUPAC Name	1-[(E)-2-(2,4-dimethoxyphenyl)ethenyl]-3,5-dimethoxybenzene
Synonym	2,3',4,5'-Tetramethoxystilbene; 2,4,3',5'-tetramethoxystilbene; 3,5,2',4'-tetramethoxy-trans-stilbene; AC1NS4S6; Oxyresveratrol tetramethyl ether
Solubility	100mg/mL in DMSO 6mg/mL in MeOH

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	T503720 MSDS PDF
Info Sheet	T503720 Info Sheet PDF

References

Kim S., Hyojin K., et al. Design, Synthesis, and Discovery of Novel trans-Stilbene Analogues as Potent and Selective Human Cytochrome P450 1B1 Inhibitors. J Med Chem. 45(1):160-164 (2001). PMID: 11754588.

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TMS

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