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Diflunisal

Product ID D3322
Cas No. 22494-42-4
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $64.90 In stock
10 g $129.60 In stock
50 g $463.00 In stock
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  • Description
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Description

Diflunisal is a long-acting non-steroidal anti-inflammatory drug (NSAID) that is clinically used to treat arthritis and dental pain. Diflunisal inhibits COX-1 and COX-2, exhibiting anti-inflammatory, antipyretic, analgesic, and antiviral activities. In vitro, diflunisal inhibits docking of HIV-1 to LEDGF/p75, preventing viral integration.

Product Info

Cas No.

22494-42-4

Purity

≥98%

Formula

C13H8F2O3

Formula Wt.

250.20

Chemical Name

2',4'-Difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid

IUPAC Name

5-(2,4-difluorophenyl)-2-hydroxybenzoic acid

Synonym

Adomal, Difludol, Dolisal, Dolobid, Dolobis, Flovacil, Fluniget, Fluodonil

Melting Point

210-211°C

Solubility

Sparingly soluble in water.

Appearance

White Crystalline Powder or Colorless Crystals

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

D3322 MSDS PDF

Info Sheet

D3322 Info Sheet PDF

References

Hu G, Li X, Sun X, et al. Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking. J Mol Model. 2012 Dec;18(12):4995-5003. PMID: 22733274.

Lawton GM, Chapman PJ. Diflunisal--a long-acting non-steroidal anti-inflammatory drug. A review of its pharmacology and effectiveness in management of postoperative dental pain. Aust Dent J. 1993 Aug;38(4):265-71. PMID: 8216032.

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