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SR-717 Lithium Salt

Product ID S680017
Cas No. 2375421-09-1
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $65.00 In stock
25 mg $200.00 In stock
100 mg $525.00 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

SR-717 Lithium salt is a STING agonist.

Product Info

Cas No.

2375421-09-1

Purity

≥98%

Formula

C15H8F2LiN5O3

Formula Wt.

351.20

IUPAC Name

lithium;4,5-difluoro-2-[(6-imidazol-1-ylpyridazine-3-carbonyl)amino]benzoate

Synonym

SR717 Lithium

Appearance

Grayish-white solid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

S680017 Info Sheet PDF

References

Huang R, Shi Q, Zhang S, et al. Inhibition of the cGAS-STING pathway attenuates lung ischemia/reperfusion injury via regulating endoplasmic reticulum stress in alveolar epithelial type II cells of rats. J Inflamm Res. 2022 Sep 5;15:5103-5119. PMID: 36091334

Wang L, Zhang Y, Ren Y, et al. Pharmacological targeting if cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis. Eur J Pharmacol. 2022 Oct 15;932:175241

Chin E, Yu C, Vartabedian V, et al. Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science. 2020 Aug 21;369(6506):993-999. PMID: 32820126

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