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Growth Hormone Releasing Peptide 2

Growth Hormone Releasing Peptide 2

Product ID G2968
Cas No. 158861-67-7
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $147.00 Please Inquire
1 mg $249.50 Please Inquire
2.5 mg $441.50 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Growth hormone releasing peptide 2 (GHRP-2) is a peptide that induces the release of growth hormone and secretion of cAMP, adrenocorticotropic hormone (ACTH), and insulin-like growth factor 1 (IGF-1) in vitro and in vivo through binding the ghrelin receptor. GHRP-2 exhibits orexigenic, gastrointestinal modulatory, antioxidative, and anti-inflammatory activities. In animal models, GHRP-2 increases food intake and inhibits gastrointestinal contractility. GHRP-2 stimulates release of ghrelin and also decreases morphine-induced analgesia in various animal models. In vitro and in vivo, GHRP-2 decreases levels of superoxide anions and lipoxygenase, decreasing production of peroxides and accumulation of lipids. In animal models of lung injury, GHRP-2 attenuates LPS-induced increases in TNF-α and IL-6 and suppresses activation of NF-κB.

Product Info

Cas No.

158861-67-7

Purity

≥95%

Formula

C45H54O6N9

Formula Wt.

818.0

IUPAC Name

6-amino-2-[[2-[[2-[2-[(2-amino-3-naphthalen-2-ylpropanoyl)amino]propanoylamino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-(2-aminopropanoyl)hexanamide

Synonym

Pralmorelin, KP 102, GHRP-2

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G2968 MSDS PDF

Info Sheet

G2968 Info Sheet PDF

References

Zeng P, Chen JX, Yang B, et al. Attenuation of systemic morphine-induced analgesia by central administration of ghrelin and related peptides in mice. Peptides. 2013 Dec;50:42-9. PMID: 24113541.

Peroni CN, Hayashida CY, Nascimento N, et al. Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient little mice. Clinics (Sao Paulo). 2012;67(3):265-72. PMID: 22473409.

Tsukamoto N, Otsuka F, Miyoshi T, et al. Functional interaction of bone morphogenetic protein and growth hormone releasing peptide in adrenocorticotropin regulation by corticotrope cells. Mol Cell Endocrinol. 2011 Sep 15;344(1-2):41-50. PMID: 21742013.

Li G, Li J, Zhou Q, et al. Growth hormone releasing peptide-2, a ghrelin agonist, attenuates lipopolysaccharide-induced acute lung injury in rats. Tohoku J Exp Med. 2010 Sep;222(1):7-13. PMID: 20805679.

Titterington JS, Sukhanov S, Higashi Y, et al. Growth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis. Endocrinology. 2009 Dec;150(12):5478-87. PMID: 19819949.

Kudoh K, Shibata C, Funayama Y, et al. The effect of growth hormone releasing peptide-2 on upper gastrointestinal contractile activity and food intake in conscious dogs. J Gastroenterol. 2009;44(4):297-304. PMID: 19271111.

Custom Order

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  • This field is for validation purposes and should be left unchanged.

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