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AZD-0156

Product ID A985120
Cas No. 1821428-35-6
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $86.50 In stock
25 mg $278.20 In stock
100 mg $587.20 Please Inquire
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  • Product Info
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  • Description
  • Product Info
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  • Downloads
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Description

AZD-0156 is an inhibitor of the ataxia-telangiectasia mutated (ATM) kinase. ATM is a member of the PIKK family, a family of kinases that are activated in response to DNA damage. ATM inhibition promotes survival in mice with chromosomal rearrangements of the MLL oncogene, a subtype of acute myeloid leukemia.

Product Info

Cas No.

1821428-35-6

Purity

≥98%

Formula

C26H31N5O3

Formula Wt.

461.57

IUPAC Name

8-{6-[3-(Dimethylamino)propoxy]-3-pyridinyl}-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one

Synonym

AZD 0156, AZD0156

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A985120 MSDS PDF

Info Sheet

A985120 Info Sheet PDF

References

Moragdo-Palacin I., Day A., et al. Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML. Sci Signal. 9(445):ra91 (2016). PMID: 27625305.

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