Description
This naphthalene exhibits anticancer activity; in fibrosarcoma and breast cancer cells, it increases expression of STAT1 and IFN regulatory factor 1 and enhances the ability of IFNγ to inhibit cell proliferation.
Product Unit Size | Cost | Quantity | Stock |
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This naphthalene exhibits anticancer activity; in fibrosarcoma and breast cancer cells, it increases expression of STAT1 and IFN regulatory factor 1 and enhances the ability of IFNγ to inhibit cell proliferation.
Cas No. | 65182-56-1 |
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Purity | ≥98% |
Formula | C14H10N2O |
Formula Wt. | 222.24 |
IUPAC Name | 6-(1H-1,8-naphthyridin-2-ylidene)cyclohexa-2,4-dien-1-one |
Solubility | Ethanol (7 mg/mL), DMSO (50 mg/mL) |
Appearance | Red Crystals |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Lynch RA, Etchin J, Battle TE, et al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61. PMID: 17283162.