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Chloramphenicol

Product ID C2844
Cas No. 56-75-7
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $44.00 In stock
10 g $61.80 In stock
50 g $176.50 In stock
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  • Product Info
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  • References
  • Description
  • Product Info
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  • Downloads
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Description

Chloramphenicol is an antibiotic compound that binds the 50S subunit of the bacterial ribosome, suppressing mitochondrial protein translation; it inhibits peptidyl transferase, preventing translocation. Chloramphenicol exhibits antibacterial activity against Streptomyces.

Product Info

Cas No.

56-75-7

Purity

≥98%

Formula

C11H12Cl2N2O5

Formula Wt.

323.13

Chemical Name

Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1- (hydroxymethyl)-2-(4-nitrophenyl)ethyl)-

IUPAC Name

2,2-dichloro-N-[(1R,2R)-1, 3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

Synonym

Chloromyxin, Ophthochlor, Ophthocort.

Melting Point

150.5-151.5°C

Solubility

Slightly soluble in water (2.5 mg/mL). Very soluble in methanol, ethanol, ethyl acetate, acetone.

Appearance

White or Yellowish White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C2844 MSDS PDF

Info Sheet

C2844 Info Sheet PDF

References

Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470.

Rajesh T, Song E, Lee BR, et al. Increased sensitivity to chloramphenicol by inactivation of manB in Streptomyces coelicolor. J Microbiol Biotechnol. 2012 Oct;22(10):1324-9. PMID: 23075781.

Wilson DN. On the specificity of antibiotics targeting the large ribosomal subunit. Ann N Y Acad Sci. 2011 Dec;1241:1-16. PMID: 22191523.

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