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13-TES-Baccatin III

13-TES-Baccatin III

Product ID T1012
Cas No. 208406-86-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $336.30 In stock
5 mg $1,201.90 In stock
10 mg $1,931.80 In stock
25 mg $3,577.20 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

An impurity of the chemotherapy drug paclitaxel.

Product Info

Cas No.

208406-86-4

Purity

≥98%

Formula

C37H52O11Si

Formula Wt.

700.90

Chemical Name

Baccatin III 13-O-(triethylsilanyl)

IUPAC Name

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-15-triethylsilyloxy-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

Synonym

Baccatin III, 13-TES; (2aS,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-9-((triethylsilyl)oxy)-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate

Appearance

White solid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T1012 MSDS PDF

Info Sheet

T1012 Info Sheet PDF

References

Nicolaou K, Yang Z, Liu J, et al. Total synthesis of taxol. Nature. 1994 Feb 17;367(6464):630-634. PMID: 7906395.

Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.

Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.

Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.

Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.

Custom Order

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