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Eledoisin

Product ID E4416
Cas No. 69-25-0
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $74.10 In stock
2 mg $126.00 In stock
5 mg $222.50 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Eledoisin is a tachykinin analog of substance P. Eledoisin binds neurokinin receptors, exhibiting vasodilatory and bronchoconstrictive activities. At low doses, eledoisin stimulates gastric acid secretion; at high doses, this process is inhibited. Eledoisin causes vasodilation in vivo and induces gastric contractions. Additionally, this peptide contracts smooth muscles, such as those in the bladder.

Product Info

Cas No.

69-25-0

Purity

≥95%

Formula

C54H85N13O15S

Formula Wt.

1188.44

IUPAC Name

(3S)-3-[[(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5- oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino] hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S, 3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl] amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1- oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl] amino]-4-oxobutanoic acid

Synonym

Eledone peptide.

Solubility

Soluble in water (0.2 mg/mL), DMSO.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E4416 MSDS PDF

Info Sheet

E4416 Info Sheet PDF

References

Tucci P, Bolle P, Severini C. Effects of natural tachykinins on ovine lower urinary tract smooth muscle. J Auton Pharmacol. 2001 Apr;21(2):79-84. PMID: 11679016.

Ito S, Ohta T, Honda H, et al. Gastric vasodilator and motor responses to splanchnic stimulation and tachykinins in the dog. Gen Pharmacol. 1993 Mar;24(2):291-8. PMID: 7683299.

Holstein B, Cederberg C. Effects of tachykinins on gastric acid and pepsin secretion and on gastric outflow in the Atlantic cod, Gadus morhua. Am J Physiol. 1986 Mar;250(3 Pt 1):G309-15. PMID: 2420206.

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