Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
Product Unit Size | Cost | Quantity | Stock |
---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
Cas No. | 58131-57-0 |
---|---|
Purity | ≥98% |
Formula | C11H13N5O4 |
Formula Wt. | 279.25 |
Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
Appearance | Orange to red solid |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
Fluoroquinolone; topoisomerase IV and bacterial...
Endogenous coenzyme, unit of cellular energy, r...
Nitrosourea, DNA cross-linker.
Aureothricin is a member of the dithiolopyrrolo...
pan-PI3K inhibitor
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Impurity of diclofenac
B-Raf and c-Raf inhibitor.
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Endogenous opioid peptide; δOR and μOR agonis...
EphB4 inhibitor.
Triazole; demethylation inhibitor.
Calcineurin inhibitor, potential TRPV1 agonist....
Calcitonin-family peptide, involved in vasodila...
Taxane found in Taxus; DNA polymerase inhibitor...
Antimicrobial peptide found in Trichoderma, ind...
α4β2 nAChR desensitizer, delayed-rectifier vo...
Triadimefon metabolite; mutagen.
Snake venom found in Bothrops alternatus urutu....
IGF-1R and InsR inhibitor.