• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Nociceptin

Nociceptin

Product ID N5210
Cas No. 170713-75-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $199.50 In stock
2.5 mg $315.00 In stock
5 mg $483.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Nociceptin is an endogenous neuropeptide that binds the nociceptin (NOP) receptor, considered the ‘fourth’ opioid receptor subtype. Nociceptin displays anti-opioid activity, modulating nociception and exhibiting anti-analgesic properties in vivo. In the amygdala, nociceptin displays neuromodulatory activity, decreasing glutamate release. Additionally, nociceptin inhibits the activity of POMC neurons and modulates GIRK channel signaling, altering animal mating behavior.

Product Info

Cas No.

170713-75-4

Purity

≥98%

Formula

C79H129N27O22

Formula Wt.

1809.1

Chemical Name

Orphanin FQ

Solubility

Soluble in water, acid.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

N5210 MSDS PDF

Info Sheet

N5210 Info Sheet PDF

References

Borgquist A, Rivas VM, Kachani M, et al. Gonadal Steroids Differentially Modulate the Actions of Orphanin FQ/Nociceptin at A Physiologically Relevant Circuit Controlling Female Sexual Receptivity. J Neuroendocrinol. 2014 May;26(5):329-40. PMID: 24617903.

Kallupi M, Varodayan FP, Oleata CS, et al. Nociceptin/orphanin FQ decreases glutamate transmission and blocks ethanol-induced effects in the central amygdala of naive and ethanol-dependent rats. Neuropsychopharmacology. 2014 Apr;39(5):1081-92. PMID: 24169802.

Okuda-Ashitaka E, Minami T, Tachibana S, et al. Nocistatin, a peptide that blocks nociceptin action in pain transmission. Nature. 1998 Mar 19;392(6673):286-9. PMID: 9521323.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A0778

    ABT-737

    BH3 mimetic; Bcl-2, Bxl-xl, Bcl-w inhibitor.

    ≥98%
  • O1178

    n-Octyl-3-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥98%
  • C6982

    Crustacean Cardioactive Peptide

    Neuropeptide hormone found in arthropods.

    ≥95%
  • A2420

    A-769662

    AMPK activator.

    ≥98%
  • S680017

    SR-717 Lithium Salt

    STING agonist

    ≥98%
  • C022682

    2-Carbomethoxy-3-thiophenesulfonyl Chloride

    Building block

    ≥98%
  • A8812

    AWD 131-138

    GABA-A positive modulator.

    ≥99%
  • C8017

    Cuelure

    Hormonal attractant for male Bactrocera flies.<...

    ≥97%
  • T2402

    TG100-115

    p110δ and p110γ PI3K inhibitor.

    ≥98%
  • V9228

    VX-765

    NLRP3 and caspase-1 inhibitor.

    ≥98%
  • G4481

    Glucagon-like Peptide I Amide (7-36), human

    Endogenous peptide hormone, GLP-1 fragment, inv...

    ≥95%
  • C3352

    Cinacalcet Hydrochloride

    Ca2+-sensing receptor agonist.

    ≥99%
  • A0971

    Adrenocorticotropic Hormone (4-10), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • R2815

    Recombinant HIV-1 “0” group consensus

    Recombinant HIV-1 antigen fragment.

    ≥95%
  • G7443

    GSK-429286A

    ROCK1/2 inhibitor, potential RSK and p70S6K inh...

    ≥98%
  • T0098

    10-Deacetyltaxol C

    Diterpene found in Taxus; potential microtubule...

    ≥97%
  • B4517

    Bleomycin A5 Hydrochloride

    Glycopeptide, induces DNA strand breaks.

    ≥90%
  • M1676

    Methotrexate Hydrate

    DHF reductase inhibitor.

    ≥98%
  • A4445

    Allopurinol

    Purine (hypoxanthine) analog; xanthine oxidase ...

    ≥98%
  • P0344

    Palbociclib Isethionate

    CDK4/6 inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only