Description
5-Methoxy indole is the core structure of melatonin; it may be an endogenous ligand for PPARγ and may act as an agonist at 5-HT3 receptors.
5-Methoxyindole
Product ID M1680
Cas No. 1006-94-6
Purity ≥98%
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Product Info
| Cas No. | 1006-94-6 |
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| Purity | ≥98% |
| Formula | C9H9NO |
| Formula Wt. | 147.17 |
| Chemical Name | 5-Methoxy-1H-indole |
| IUPAC Name | 5-methoxy-1H-indole |
| Synonym | Femedol |
| Melting Point | 52-55°C |
| Solubility | Insoluble in water. |
| Appearance | Slightly yellow crystalline |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Kong M, Liang J, Ali Q, et al. 5-Methoxyindole, a chemical homolog of melatonin, adversely affects the phytopathogenic fungus Fusarium graminearum. Int J Mol Sci. 2021 Oct 12;22(20):10991. PMID: 34681652.
Czimmerer Z, Varga T, Poliska S, et al. Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages. Immunobiology. 2012 Dec;217(12):1301-14. PMID: 22954708.
Koike T, Hoashi Y, Takai T, et al. 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists. J Med Chem. 2011 May 12;54(9):3436-44. PMID: 21473625.