Description
CASIN is an inhibitor of the Cdc42 GTPase; it may exhibit neuroprotective activity by stimulating the rejuvenation of aged hematopoietic stem cells.
CASIN is an inhibitor of the Cdc42 GTPase; it may exhibit neuroprotective activity by stimulating the rejuvenation of aged hematopoietic stem cells.
Cas No. | 425399-05-9 |
---|---|
Purity | ≥97% |
Formula | C20H22N2O |
Formula Wt. | 306.41 |
Chemical Name | 2-[(6-Phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino]ethanol |
IUPAC Name | 2-[(6-Phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino]ethanol |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Florian MC, Dörr K, Niebel A, et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell. 2012 May 4;10(5):520-30. PMID: 22560076.
Peterson JR, Lebensohn AM, Pelish HE, et al. Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components. Chem Biol. 2006 Apr;13(4):443-52. PMID: 16632257.
Penciclovir prodrug, nucleoside (guanosine) ana...
Terpene lactone found in Ginkgo; GlyR antagonis...
Glucose metabolism inhibitor, N-linked glycosyl...
Wnt signaling inhibitor.
Aurora kinase A inhibitor
Aromatic 1,3-diketone acetylacetone derivative ...
Sesquiterpene lactone found in Thapsia, used to...
α2-adrenergic agonist.
Pt-based DNA cross-linker.
Protease inhibitor
Bosutinib isomer; Src and Abl inhibitor.
Pt-based DNA cross-linker.
Caspase 3 substrate.
Alkaloid found in Catharanthus, precursor in sy...
PI3K and mTOR inhibitor.
PIKfyve inhibitor.
Rapamycin analog
Endogenous quaternary ammonium, required for fa...
Synthesis impurity
Endogenous calcitonin-family peptide, involved ...