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n-Butyric Acid

n-Butyric Acid

Product ID B8275
Cas No. 107-92-6
Purity ≥98%
Product Unit SizeCostQuantityStock
10 ml $77.80 In stock
100 ml $108.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Butyric acid is a fatty acid found in many dairy products that exhibits anticancer activity. Butyric acid inhibits histone deacetylases (HDACs) and induces apoptosis and G1 phase cell cycle arrest in glioma cells. Additionally, butyric acid stimulates epithelial cell proliferation at low doses and inhibits proliferation at high doses.

Product Info

Cas No.

107-92-6

Purity

≥98%

Formula

C4H8O2

Formula Wt.

88.10

IUPAC Name

butanoic acid

Synonym

Butanoic acid, Butyric acid, Ethylacetic acid

Melting Point

-7°C

Solubility

Miscible with water, alcohol or ether.

Appearance

Colorless liquid

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

B8275 MSDS PDF

Info Sheet

B8275 Info Sheet PDF

References

Kim SW, Hooker JM, Otto N, et al. Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET. Nucl Med Biol. 2013 Oct;40(7):912-8. PMID: 23906667.

Inagaki A, Sakata T. Dose-dependent stimulatory and inhibitory effects of luminal and serosal n-butyric acid on epithelial cell proliferation of pig distal colonic mucosa. J Nutr Sci Vitaminol (Tokyo). 2005 Jun;51(3):156-60. PMID: 16161765.

Komata T, Kanzawa T, Nashimoto T, et al. Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells. Int J Oncol. 2005 May;26(5):1345-52. PMID: 15809727.

Custom Order

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